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Products Details
Product Description
– BChE-IN-19 (Compound 7b) is a para-substituted derivative of indone (7b) with inhibitory activity of butyryl cholinesterase (BChE) (IC50=0.04 μM). BChE-IN-19 improves cholinergic scheduling in the nervous system. BChE-IN-19 can be used against Alzheimer’s disease[1].
Web ID
– HY-156031
Shipping
– Room temperature
Molecular Formula
– C25H31NO5
References
– [1]Etemadi A, et al. Design, Synthesis, and Biological Evaluation of Novel Indanone Derivatives as Cholinesterase Inhibitors for Potential Use in Alzheimer’s Disease. Chem Biodivers. 2023 Aug;20(8):e202300075.
Molecular Weight
– 425.52
SMILES
– O=C1C(CC2=CC=C(OCCCN3CCOCC3)C=C2)CC4=C1C=C(OC)C(OC)=C4
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Isoform
– BChE
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
