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Products Details
Product Description
– BChE-IN-16 (compound 87) is a highly potent BChE inhibitor with an IC50 of 3.8 nM for hBChE. BChE-IN-16 has low cytotoxicity, potential CNS permeability, unique adaptability and can be used in Alzheimer’s disease (AD) research.
Web ID
– HY-149243
Shipping
– Room temperature
Molecular Formula
– C28H32FNO2
References
– [1]Pidany F, et al. Highly selective butyrylcholinesterase inhibitors related to Amaryllidaceae alkaloids – Design, synthesis, and biological evaluation. Eur J Med Chem. 2023 Apr 5;252:115301.
Molecular Weight
– 433.56
SMILES
– COC1=CC=CC(CN(C2CCC2)CCCC3=C(C=CC=C3)F)=C1OCC4=CC=CC=C4
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Isoform
– BChE
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
