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Products Details
Product Description
– BChE-IN-12 (compound 12) is a potent butyrylcholinesterase (BChE) non-competitive inhibitor with an IC50 value of 2.3 μM. BChE-IN-12 can be isolated from Bletilla striata. BChE-IN-12 can be used for the research of Alzheimer’s disease (AD)[1].
Web ID
– HY-N10489
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C31H30O5
References
– [1]Liu Y, et al. Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors. Sci Rep. 2022 Aug 11;12(1):13649.
CAS Number
– 136966-86-4
Molecular Weight
– 482.57
SMILES
– OC1=CC(OC)=C2C3=CC=C(O)C(CC4=CC=C(O)C=C4)=C3C=CC2=C1CC5=CC=C(O)C=C5.CC
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Isoform
– BChE
Pathway
– Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
