Products Details

Product Description

– BChE-IN-11 (compound 10) is a potent, selective and non-competitive BChE (butyrylcholinesterase) inhibitor, with an IC50 of 2.1 μM. BChE-IN-11 can be used for Alzheimer’s disease (AD) research[1].

Web ID

– HY-N10488

Shipping

– Room temperature

Applications

– Neuroscience-Neurodegeneration

Molecular Formula

– C22H18O4

References

– [1]Liu Y, et al. Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors. Sci Rep. 2022 Aug 11;12(1):13649.

CAS Number

– 133740-30-4

Molecular Weight

– 346.38

SMILES

– OC1=CC(OC)=C2C3=CC=C(O)C=C3C=CC2=C1CC4=CC=C(O)C=C4

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Cholinesterase (ChE)

Isoform

– AChE;BChE

Pathway

– Neuronal Signaling

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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