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BC11-38
$80 – $670
Products Details
Product Description
– BC11-38 is a potent, selective, and biologically active PDE11 inhibitor, with IC50s of 0.28 µM and >100 µM for PDE11 and PDE1-10, respectively. BC11-38 elevates cAMP levels, PKA-mediated ATF-1 phosphorylation, and cortisol production in H295R cells[1].
Web ID
– HY-108618
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C15H16N2OS2
References
– [1]Ceyhan O, et al. Identification of biologically active PDE11-selective inhibitors using a yeast-based high-throughput screen. Chem Biol. 2012;19(1):155-163.
CAS Number
– 686770-80-9
Molecular Weight
– 304.43
Compound Purity
– 98.13
SMILES
– O=C1C2=C(CCS2)N=C(SCCC)N1C3=CC=CC=C3
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– DMSO : 33.33 mg/mL (ultrasonic)
Target
– Phosphodiesterase (PDE)
Isoform
– PDE10;PDE11
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
