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BAY 60-2770
$130 – $1,580
Products Details
Product Description
– BAY 60-2770 is a potent, selective, and orally active soluble guanylyl cyclase (sGC) activator. BAY 60-2770 increases the activity of sGC in a nitric oxide-independent manner. BAY 60-2770 shows antifibrotic effect[1][2].
Web ID
– HY-113926
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C35H33F4NO5
References
– [1]Knorr A, et al. Nitric oxide-independent activation of soluble guanylate cyclase by BAY 60-2770 in experimental liver fibrosis. Arzneimittelforschung. 2008;58(2):71-80.|[2]Leiria LO, et al. The soluble guanylyl cyclase activator BAY 60-2770 ameliorates overactive bladder in obese mice. J Urol. 2014 Feb;191(2):539-47.
CAS Number
– 1027642-43-8
Molecular Weight
– 623.63
Compound Purity
– 98.97
SMILES
– O=C(O)C1=CC=C(CN(CCCCC(O)=O)CCC2=CC(F)=CC=C2OCC3=CC=C(C4=CC=C(C(F)(F)F)C=C4)C=C3)C=C1
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 16.67 mg/mL (ultrasonic)
Target
– Guanylate Cyclase
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
