Download Files:
Products Details
Product Description
– Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109. BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.
Web ID
– HY-100029B
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C18H13ClF3N3O2
References
– [1]Weber O, et al. Inhibition of human hepatitis B virus (HBV) by a novel non-nucleosidic compound in a transgenic mouse model. Antiviral Res. 2002 May;54(2):69-78.|[2]Stray SJ, et al. BAY 41-4109 has multiple effects on Hepatitis B virus capsid assembly. J Mol Recognit. 2006 Nov-Dec;19(6):542-8.|[3]Wu GY, et al. Inhibition of hepatitis B virus replication by Bay 41-4109 and its association with nucleocapsid disassembly. J Chemother. 2008 Aug;20(4):458-67.
CAS Number
– 476617-51-3
Molecular Weight
– 395.76
Compound Purity
– 89.59
SMILES
– O=C(C1=C(C)N=C(C2=NC=C(F)C=C2F)N[C@@H]1C3=CC=C(F)C=C3Cl)OC
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : ≥ 37 mg/mL
Target
– HBV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
