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BAY-299
$55 – $539
Products Details
Product Description
– BAY-299 is a very potent, dual inhibitor with IC50s of 67 nM for BRPF2 bromodomains (BD), 8 nM for TAF1 BD2, and 106 nM for TAF1L BD2.
Web ID
– HY-107424
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H23N3O4
References
– [1]Bouché L, et al. Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains. J Med Chem. 2017 May 11;60(9):4002-4022.
CAS Number
– 2080306-23-4
Molecular Weight
– 429.47
Compound Purity
– 99.24
SMILES
– O=C(N1C2=C(C)C=C(N(C)C3=O)C(N3C)=C2)C4=CC=C(CCCO)C5=C4C(C1=O)=CC=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 25 mg/mL (ultrasonic;warming)
Target
– Epigenetic Reader Domain
Isoform
– BRPF1;BRPF2;BRPF3
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
