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BAY-298
Price range: 3,213 CAD through 4,829 CAD
Products Details
Product Description
– BAY-298 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC50s of 96 nM, 23 nM, and 78 nM for hLH (human LH), rLH (rat LH), and cLH (cynomolgus monkey LH), respectively. It is the first nanomolar hLH-R antagonist that reduces sex hormone levels in vivo [1].
Web ID
– T10469
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H21ClFN3O2
References
– Wortmann L, et al. Discovery of BAY-298 and BAY-899: Tetrahydro-1,6-naphthyridine-Based, Potent and Selective Antagonists of the Luteinizing Hormone Receptor Which Reduce Sex Hormone Levels In Vivo. J Med Chem. 2019 Oct 31.
CAS Number
– 2471978-97-7
Molecular Weight
– C27H21ClFN3O2
SMILES
– Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1
Target
– Others
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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