BAY-1436032

$90$980

Products Details

Product Description

– BAY-1436032 is a novel pan-mutant isocitrate dehydrogenase 1 (IDH1) inhibitor.

Web ID

– HY-100020

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C26H30F3N3O3

References

– [1]Chaturvedi A, et al. Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo. Leukemia. 2017 Oct;31(10):2020-2028.

CAS Number

– 1803274-65-8

Molecular Weight

– 489.53

Compound Purity

– 99.48

SMILES

– O=C(O)CCC1=CC=C2C(N=C(NC3=CC=C(OC(F)(F)F)C=C3)N2[C@H]4CC(C)(C)C[C@@H](C)C4)=C1

Clinical Information

– Phase 1

Research Area

– Cancer

Solubility

– DMSO : 125 mg/mL (ultrasonic;warming)

Target

– Isocitrate Dehydrogenase (IDH)

Isoform

– IDH1

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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