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Products Details
Product Description
– BAY 1217224 is a neutral, non-proagent Thrombin inhibitor with good oral pharmacokinetics.
Web ID
– HY-142661
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C24H27ClFN3O5
References
– [1]Hillisch A, et al. Design, Synthesis, and Pharmacological Characterization of a Neutral, Non-Prodrug Thrombin Inhibitor with Good Oral Pharmacokinetics. J Med Chem. 2020 Nov 12;63(21):12574-12594.
CAS Number
– 1639886-32-0
Molecular Weight
– 491.94
SMILES
– COC1=C2C(N=C(O2)N[C@@H](C3=CC(Cl)=CC=C3)CF)=CC(C(N4[C@H](CO[C@H](C4)C)CCO)=O)=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Thrombin
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
