Products Details

Product Description

– BAY 1217224 is a neutral, non-proagent Thrombin inhibitor with good oral pharmacokinetics.

Web ID

– HY-142661

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C24H27ClFN3O5

References

– [1]Hillisch A, et al. Design, Synthesis, and Pharmacological Characterization of a Neutral, Non-Prodrug Thrombin Inhibitor with Good Oral Pharmacokinetics. J Med Chem. 2020 Nov 12;63(21):12574-12594.

CAS Number

– 1639886-32-0

Molecular Weight

– 491.94

SMILES

– COC1=C2C(N=C(O2)N[C@@H](C3=CC(Cl)=CC=C3)CF)=CC(C(N4[C@H](CO[C@H](C4)C)CCO)=O)=C1

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Thrombin

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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