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Products Details
Product Description
– BAY 1003803 is a glucocorticoid receptor agonist for the topical research of psoriasis or severe atopic dermatitis.
Web ID
– HY-145351
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H18ClF5N2O4
References
– [1]Berger M, et al. Discovery of the potent non-steroidal glucocorticoid receptor modulator BAY 1003803 as clinical candidate. Bioorg Med Chem Lett. 2020 Aug 15;30(16):127298.
CAS Number
– 1152781-51-5
Molecular Weight
– 492.82
SMILES
– FC1=CC(N[C@@H](C2=C(C(F)=C(C=C2)OC)Cl)[C@](C(F)(F)F)(O)COC)=C3C(NC(C=C3)=O)=C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Glucocorticoid Receptor
Pathway
– Immunology/Inflammation;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
