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Product Description
– Batracylin (NSC320846) is a potent DNA Topoisomerases I and DNA Topoisomerases II inhibitor. Batracylin shows cytotoxicity and antiproliferative activity. Batracylin induces DNA breaks[1].
Web ID
– HY-119892
Shipping
– Room temperature
Molecular Formula
– C15H11N3O
References
– [1]Rao VA, et al. Batracylin (NSC 320846), a dual inhibitor of DNA topoisomerases I and II induces histone gamma-H2AX as a biomarker of DNA damage. Cancer Res. 2007 Oct 15;67(20):9971-9.
CAS Number
– 67199-66-0
Molecular Weight
– 249.27
SMILES
– O=C1C2=C(C=CC=C2)C3=NC4=C(CN31)C=C(C=C4)N
Clinical Information
– Phase 1
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Topoisomerase
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
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