BAN ORL 24

$101$1,056

Products Details

Product Description

– BAN ORL 24 is a nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) antagonist. BAN ORL 24 has antagonistic effect for nociceptin (NOP) receptor with KI value of 0.24 nM in CHO cell. BAN ORL 24 can be used for the research of cancer and analgesic[1].

Web ID

– HY-13222

Storage Temperature

– -20°C (Powder, protect from light, stored under nitrogen)

Shipping

– Blue Ice

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C27H37Cl2N3O2

References

– [1]Tao Hou, et al. Label-free cell phenotypic study of opioid receptors and discovery of novel mu opioid ligands from natural products. J Ethnopharmacol|[2]Chao, et al. BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine. Neuropharmacology 166, 107678 (2020).|[3]Fischetti et al (2009) Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist compound 24. Eur.J.Pharmacol. 614 50.

CAS Number

– 1401463-54-4

Molecular Weight

– 506.51

Compound Purity

– 98.09

SMILES

– O=C([C@@H]1N(CC2=CC=CC=C2)CCC1)NCCCN3CCC4(CC3)OCC5=C4C=CC=C5.[H]Cl.[H]Cl

Clinical Information

– No Development Reported

Research Area

– Cancer; Neurological Disease

Solubility

– DMSO : 200 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)

Target

– Opioid Receptor

Isoform

– NOP Receptor/ORL1

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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