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Bamocaftor
$450 – $1,980
Products Details
Product Description
– Bamocaftor (VX-659) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector designed to restore F508del-CFTR protein function. Bamocaftor can be used combine with Tezacaftor and Ivacaftor in cystic fibrosis research[1].
Web ID
– HY-126394
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C28H32F3N5O4S
References
– [1]Ghelani DP, et al. Emerging Cystic Fibrosis Transmembrane Conductance Regulator Modulators as New Drugs for Cystic Fibrosis: A Portrait of in Vitro Pharmacology and Clinical Translation.
CAS Number
– 2204245-48-5
Molecular Weight
– 591.64
Compound Purity
– 99.09
SMILES
– O=C(C1=CC=C(N2N=C(OCCC3(C(F)(F)F)CC3)C=C2)N=C1N4C(C)(C)C[C@H](C)C4)NS(=O)(C5=CC=CC=C5)=O
Clinical Information
– Phase 2
Research Area
– Endocrinology
Solubility
– DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– CFTR
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
