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Balsalazide
$76 – $672
Products Details
Product Description
– Balsalazide could suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway.
Web ID
– HY-B0667
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C17H15N3O6
References
– [1]Do EJ, et al. Suppression of colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway by balsalazide and VSL#3. J Gastroenterol Hepatol. 2016 Aug;31(8):1453-61.|[2]Kruis W, et al. Low dose balsalazide (1.5 g twice daily) and mesalazine (0.5 g three times daily) maintained remission of ulcerative colitis but high dose balsalazide (3.0 g twice daily) was superior in preventing relapses. Gut, 2001. 49(6): p. 783-789.
CAS Number
– 80573-04-2
Molecular Weight
– 357.32
Compound Purity
– 99.34
SMILES
– O=C(O)C1=CC(/N=N/C2=CC=C(C(NCCC(O)=O)=O)C=C2)=CC=C1O
Clinical Information
– Launched
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 1M NaOH : 50 mg/mL (ultrasonic;adjust pH to 12 with NaOH)|DMSO : 100 mg/mL (ultrasonic)
Target
– Interleukin Related;STAT
Isoform
– IL-1;IL-6;STAT3
Pathway
– Immunology/Inflammation;JAK/STAT Signaling;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
