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BacPROTAC-1
SKU
HY-153575-Get quote
Category Reference compound
Tags Anti-infection;PROTAC, Bacterial;PROTACs, Infection
Products Details
Product Description
– BacPROTAC-1 is a mSA BacPROTAC degrader. BacPROTAC-1 binds mSA and ClpCNTD with high affinity (KDs of 3.9 and 2.8 μM, respectively)[1].
Web ID
– HY-153575
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C45H83N12O17PS
References
– [1]Morreale FE, et al. BacPROTACs mediate targeted protein degradation in bacteria. Cell. 2022 Jun 23;185(13):2338-2353.e18.
Molecular Weight
– 1127.25
SMILES
– O=C(NCCCC[C@H](NC(CCOCCOCCNC(CCOCCOCCNC(CCOCCOCCNC([C@H](CCCNC(NP(O)(O)=O)=N)NC(C)=O)=O)=O)=O)=O)C(N)=O)CCCC[C@@H]1SC[C@@H]([C@@H]1N2)NC2=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial;PROTACs
Pathway
– Anti-infection;PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.