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BACE2-IN-1
$170 – $800
Products Details
Product Description
– BACE2-IN-1 (compound 3l) is a highly selective BACE2 inhibitor with a Ki value of 1.6 nM. BACE2 inhibitors can be used to research of Type 2 Diabetes[1].
Web ID
– HY-136742
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C36H38F3N3O3
References
– [1]Ghosh AK, et al. Highly Selective and Potent Human β-Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X-ray Structure and Structure-Activity Relationship Studies. ChemMedChem. 2019 Mar 5. 14(5):545-560.
CAS Number
– 1676107-08-6
Molecular Weight
– 617.70
Compound Purity
– 99.34
SMILES
– O=C(C1=CC(C)=CC(C(N[C@@H](CC2=CC=CC=C2)[C@H](O)CNCC3=CC=CC(C(F)(F)F)=C3)=O)=C1)N(C)[C@@H](C4=CC=CC=C4)C
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 62 mg/mL (ultrasonic;warming)
Target
– Beta-secretase
Isoform
– BACE1;BACE2
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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