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Products Details
Product Description
– BACE-1 inhibitor 1 (Compound 8a) is a potent BACE-1 inhibitor with an IC50 of 56 nM[1].
Web ID
– HY-112297
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C17H14BrF3N4O2
References
– [1]Veenstra SJ, et al. Discovery of amino-1,4-oxazines as potent BACE-1 inhibitors. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2195-2200.
CAS Number
– 1262858-14-9
Molecular Weight
– 443.22
SMILES
– BrC1=CC=C(C(NC2=CC=C(F)C([C@@]3(C(F)F)N=C(N)COC3)=C2)=O)N=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Beta-secretase
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
