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Products Details
Product Description
– BAA473 is a bile acid analog and is a potent activator of the pyrin inflammasome that induces the secretion of interleukin 18 (IL-18) through activation of the inflammasome in both myeloid and intestinal epithelial cells[1].
Web ID
– HY-123879
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H40O5
References
– [1]Alimov I, et al. Bile acid analogues are activators of pyrin inflammasome. J Biol Chem. 2019 Mar 8;294(10):3359-3366.
CAS Number
– 27240-87-5
Molecular Weight
– 420.58
SMILES
– C[C@@]12[C@]3([H])[C@](CC[C@]1([H])C[C@@H](CC2)O)([H])[C@@]4([H])[C@]([C@@H](C3=O)O)([C@@](CC4)([H])[C@H](C)CCC(OC)=O)C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Interleukin Related
Isoform
– IL-1
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
