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B I09
$130 – $1,300
Products Details
Product Description
– B I09 is an IRE-1 RNase inhibitor, with an IC50 of 1230 nM.
Web ID
– HY-107400
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C16H17NO5
References
– [1]Ranatunga S, et al. Synthesis of novel tricyclic chromenone-based inhibitors of IRE-1 RNase activity. J Med Chem. 2014 May 22;57(10):4289-301.|[2]Tang CH, et al. Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival. J Clin Invest. 2014 Jun;124(6):2585-98.
CAS Number
– 1607803-67-7
Molecular Weight
– 303.31
Compound Purity
– 98.82
SMILES
– OC1=CC=C(C2=C(CNCC2)C3=O)C(O3)=C1C4OCCCO4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 8.33 mg/mL (ultrasonic)
Target
– IRE1
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
