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Products Details
Product Description
– Azoxystrobin-d4 is deuterium labeled Azoxystrobin. Azoxystrobin is a broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis.
Web ID
– HY-B0849S
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H13D4N3O5
References
– [1]Enock Mpofu, et al. Azoxystrobin amine: A novel azoxystrobin degradation product from Bacillus licheniformis strain TAB7. Chemosphere. 2021 Jun;273:129663. |[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 1346606-39-0
Molecular Weight
– 407.41
SMILES
– [2H]C1=C([2H])C([2H])=C([2H])C(C#N)=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=COC)=C2
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Fungal;Isotope-Labeled Compounds;Reactive Oxygen Species
Pathway
– Anti-infection;Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
