Azithromycin (hydrate)

$66$264

Products Details

Product Description

– Azithromycin hydrate is a macrolide antibiotic useful for the treatment of a number of bacterial infections.

Web ID

– HY-17506A

Storage Temperature

– 4°C (Powder, protect from light, stored under nitrogen)

Shipping

– Room Temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C38H76N2O14

Citations

– Mol Ther. 2022 Feb 18;S1525-0016(22)00102-2.|ACS Chem Biol. 2021 Dec 15.|ACS Omega. March 3, 2022.|Acta Pharm Sin B. 2021 Mar 11.|Adv Sci (Weinh). 2020 Jul 21;7(17):2001374.|Biochem Biophys Res Commun. 2020 Feb 19;522(4):862-868.|Biochem Pharmacol. 2021 Sep 30;114793.|bioRxiv. 2021 Jan 19.|COVID. 2021, 1(1), 263-275.|Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Transmissores de Hematozoários. 2020 Sep.|Invest Ophthalmol Vis Sci. 2021 Feb 1;62(2):33.|iScience. 5 January 2022, 103731.|Journal of Pharmaceutical Research International. 33(47B): 274-279, 2021.|Katedra farmakologie a toxikologie. 2020 Jul.|Patent. US20200101105A1.|Research Square Preprint. 2022 Jun.|Theranostics. 2022 Jan 1;12(3):1187-1203.|Viruses. 2019 Nov 15;11(11):1064.|Viruses. 2020 Jun 10;12(6):628.

References

– [1]Menzel M, et al. Azithromycin augments rhinovirus-induced IFNβ via cytosolic MDA5 in experimental models of asthma exacerbation. Oncotarget. 2017 Mar 18.|[2]Vandooren J, et al. Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study. PLoS One. 2017 Apr 3;12(4):e0174853.

CAS Number

– 117772-70-0

Molecular Weight

– 785.02

Compound Purity

– 98.0

SMILES

– C[C@@H]([C@@H]([C@@](C(O[C@@H]([C@@](C)(O)[C@@H]1O)CC)=O)([H])C)O[C@@](O[C@@H](C)[C@@H]2O)([H])C[C@@]2(C)OC)[C@H]([C@](O)(C[C@H](CN([C@@H]1C)C)C)C)O[C@@](O[C@H](C)C[C@@H]3N(C)C)([H])[C@@H]3O.O.O

Clinical Information

– Launched

Research Area

– Infection; Cancer

Solubility

– 10 mM in DMSO

Target

– Antibiotic;Autophagy;Bacterial;Parasite

Isoform

– Macrolide

Pathway

– Anti-infection;Autophagy

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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