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AZD5099
SKU
HY-12888-Get quote
Category Reference compound
Tags Anti-infection;Cell Cycle/DNA Damage, Bacterial;Topoisomerase, Infection
Products Details
Product Description
– AZD5099, an antibacterial agent, is a potent and selective bacterial topoisomerase II inhibitor. AZD5099 potently inhibits the infections caused by Gram-positive and fastidious Gram-negative bacteria[1].
Web ID
– HY-12888
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C21H27Cl2N5O6S
References
– [1]Gregory S Basarab, et al. Optimization of pyrrolamide topoisomerase II inhibitors toward identification of an antibacterial clinical candidate (AZD5099). J Med Chem. 2014 Jul 24;57(14):6060-82.
CAS Number
– 907543-25-3
Molecular Weight
– 548.44
SMILES
– O=C(C(N=C(N(CC[C@H]1NC(C(NC(C)=C2Cl)=C2Cl)=O)C[C@@H]1OC)S3)=C3C(O)=O)N[C@@H](C)COC
Clinical Information
– Phase 1
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial;Topoisomerase
Isoform
– Topo II
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.