AZD2906

$450$3,300

Products Details

Product Description

– AZD2906 is a selective glucocorticoid receptor (GR) agonist, increases micronucleated immature erythrocytes in the bone marrow of rats. AZD2906 shows IC50s of 2.2, 0.3, 41.6 and 7.5 nM at GR in human, rat PBMC and human, rat whole blood, respectively[1].

Web ID

– HY-113854

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C26H25FN4O3

References

– [1]Hayes JE, et al. Micronucleus induction in the bone marrow of rats by pharmacological mechanisms. I: glucocorticoid receptor agonism. Mutagenesis. 2013 Mar;28(2):227-32.

CAS Number

– 1034148-15-6

Molecular Weight

– 460.50

Compound Purity

– 99.68

SMILES

– FC1=CC=C(N2N=CC3=CC(O[C@@H]([C@@H](NC(C4CC4)=O)C)C5=CC=C(N=C5)OC)=CC=C23)C=C1

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease; Endocrinology

Solubility

– DMSO : 125 mg/mL (ultrasonic)

Target

– Glucocorticoid Receptor

Pathway

– Immunology/Inflammation;Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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