Products Details

Product Description

– AZ-TAK1, an ATP-competitive small molecule inhibitor of TAK1, dephosphorylates TAK1, p38, and IκB-α in lymphoma cell lines[1].

Web ID

– HY-153320

Shipping

– Room temperature

Molecular Formula

– C25H28FN7O2

References

– [1]Daniela Buglio, et al. Essential role of TAK1 in regulating mantle cell lymphoma survival. Blood. 2012 Jul 12;120(2):347-55.

CAS Number

– 1413440-36-4

Molecular Weight

– 477.53

SMILES

– FC1=C(C2=CN=C3C=CC=NN32)N=C(NC4=CC(OCCN5CCC(CC5)O)=CC(CC)=C4)N=C1

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– MAP3K

Pathway

– MAPK/ERK Pathway

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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