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Products Details
Product Description
– AZ-GHS-22 is a potent, non-CNS penetrant GHS-R1a inverse agonist (IC50=0.77 nM)[1].
Web ID
– HY-137061
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C27H33ClN6O5S2
References
– [1]McCoull W, et al. Identification, optimization, and pharmacology of acylurea GHS-R1a inverse agonists. J Med Chem. 2014;57(14):6128-6140.
CAS Number
– 1143020-91-0
Molecular Weight
– 621.17
SMILES
– O=C(NC(NC1=NC2=CC=C(S(=O)(CCCN3CCN(C)CC3)=O)C=C2S1)=O)C4=CC(N5CCOCC5)=CC=C4Cl
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– GHSR
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
