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Products Details
Product Description
– Axl/Mer-IN-1 (Compound 1) is an Axl/Mer receptor tyrosine kinase (Axl/Mer RTK) and CSF1R inhibitor with Kds of <0.1 μM[1].
Web ID
– HY-153012
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C25H24F3N5O5
References
– [1]Kiyean NAM, et al. Quinoline derivatives as inhibitors of axl/mer rtk and csf1r. Patent WO2019229251A1.
CAS Number
– 2394874-60-1
Molecular Weight
– 531.48
SMILES
– O=C(C1=NN(CC)C(C)=C1OCC(F)(F)F)NC2=NC=C(C=C2)OC3=C4C=C(OC)C(OC)=CC4=NC=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– c-Fms;TAM Receptor
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
