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Products Details
Product Description
– AX102 sodium is a 34 bp length nucleotide aptamer modified at the 5′ end with a 40 kDa polyethylene glycol moiety. AX102 selectively binds platelet-derived growth factor B (PDGF-B) and causes tumor vessel regression[1].
Web ID
– HY-160047
Shipping
– Room temperature
Molecular Formula
– N/A
References
– [1]Sennino B, Falcón BL, McCauley D, Le T, McCauley T, Kurz JC, Haskell A, Epstein DM, McDonald DM. Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102. Cancer Res. 2007 Aug 1;67(15):7358-67.
Molecular Weight
– N/A
SMILES
– [AX102 (sodium)]
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Platelet-derived Growth Factor (PDGF)
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
