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Products Details
Product Description
– Autotaxin-IN-6 (compound 23) is a potent autotaxin (ATX) inhibitor with an IC50 value of 30 nM. Autotaxin-IN-6 can reduce cell migration. Autotaxin-IN-6 can be used for researching anticancer[1].
Web ID
– HY-150614
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C35H54BNO6
References
– [1]Clark JM, et al. Structure-Based Design of a Novel Class of Autotaxin Inhibitors Based on Endogenous Allosteric Modulators. J Med Chem. 2022 Apr 28;65(8):6338-6351.
CAS Number
– 2800898-98-8
Molecular Weight
– 595.62
SMILES
– O[C@@H]1[C@]2([H])[C@@](CC[C@]3([C@@]2([H])CC[C@]3([H])[C@H](C)CCC(N4CCC(CC4)OC5=CC=C(C=C5)B(O)O)=O)C)([H])[C@@]6([C@](C[C@@H](CC6)O)([H])C1)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– LPL Receptor;Phosphodiesterase (PDE)
Isoform
– Autotaxin
Pathway
– GPCR/G Protein;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
