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Product Description
– AUTEN-67 (inner salt), the inner salt form of AUTEN-67 (HY-117924), is an orally active autophagy-enhancing agent and MTMR14 inhibitor with potent antiaging and neuroprotective effects. AUTEN-67 (inner salt) hampers the progression of neurodegenerative symptoms in a drosophila model of Huntington’s disease[1][2].
Web ID
– HY-128477
Shipping
– Room temperature
Molecular Formula
– C23H14N4O6S
References
– [1]Diána Papp, et al. AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects. Autophagy. 2016 Feb; 12(2): 273–286.|[2]Viktor Billes, et al. AUTEN-67 (Autophagy Enhancer-67) Hampers the Progression of Neurodegenerative Symptoms in a Drosophila model of Huntington’s Disease. J Huntingtons Dis. 2016 May 7;5(2):133-47.
CAS Number
– 301154-74-5
Molecular Weight
– 474.45
SMILES
– O=C1C([N-]S(=O)(C2=CC=C([N+]([O-])=O)C=C2)=O)=C([N+]3=CNC4=C3C=CC=C4)C(C5=C1C=CC=C5)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Autophagy
Pathway
– Autophagy
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
