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Aurora kinase inhibitor-2
$385 – $2,750
Products Details
Product Description
– Aurora kinase inhibitor-2 is a selective and ATP-competitive Aurora kinase inhibitor with IC50s of 310 nM and 240 nM for Aurora A and Aurora B, respectively[1].
Web ID
– HY-112355
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C23H20N4O3
References
– [1]Andrew A Mortlock, et al. Progress in the development of selective inhibitors of aurora kinases. Curr Top Med Chem. 2005;5(8):807-21.|[2]Nicola M Heron, et al. SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1320-3.
CAS Number
– 331770-21-9
Molecular Weight
– 400.43
Compound Purity
– 99.19
SMILES
– O=C(NC1=CC=C(NC2=C3C=C(OC)C(OC)=CC3=NC=N2)C=C1)C4=CC=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Aurora Kinase
Isoform
– Aurora A;Aurora B
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
