Products Details

Product Description

– Aurora Kinase Inhibitor-12 (Compound 1a ) is the inhibitor of aurora kinase which is a key enzyme that is implicated in tumor growth[1].

Web ID

– HY-149694

Shipping

– Room temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C28H20BrN5O3S2

References

– [1]Bathula, Sivakumar, et al. 2-Amino Thiazole Derivatives as Prospective Aurora Kinase Inhibitors against Breast Cancer: QSAR, ADMET Prediction, Molecular Docking, and Molecular Dynamic Simulation Studies. ACS Omega (2023)

Molecular Weight

– 618.52

SMILES

– OC1=C(/C=C2N=C(C3=CC=CC=C3)N(C(NCC(NC4=C(C5=CC=C(Br)C=C5)SC=N4)=O)=S)C2=O)C=CC=C1

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Aurora Kinase

Pathway

– Cell Cycle/DNA Damage;Epigenetics

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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