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Product Description
– Aurora A inhibitor 1 is a potent and selective inhibitor of Aurora A. Aurora A has been implicated in cancers of diverse histological origin and may possess oncogenic properties when overexpressed. Aurora A inhibitor 1 has the potential for the research of cancer diseases mediated by aurora a (extracted from patent WO2021147974A1, compound 49)[1].
Web ID
– HY-143713
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C25H28ClF2N5O2
References
– [1]Dai Cheng, et al. Novel heterocyclic compounds useful as aurora a selective inhibitors. Patent WO2021147974A1.
CAS Number
– 2677799-04-9
Molecular Weight
– 503.97
SMILES
– O=C([C@@]1(CC2=NC(NC3=NNC(C)=C3)=CC(C)=C2F)C[C@@H](C)N(CC4=CC=CC(Cl)=C4F)CC1)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Aurora Kinase
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
