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Products Details
Product Description
– ATX inhibitor 22 is a novel inhibitor of ATX (autotaxin) with IC50 of 218 nM but lost its inhibitory activity of LPAR1[1].
Web ID
– HY-149018
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H17Cl3F2N2O4S
References
– [1]Souvik Banerjee, et al. Molecular modelling guided design, synthesis and QSAR analysis of new small molecule non-lipid autotaxin inhibitors. Bioorg Chem. 2020 Oct; 103: 104188.
CAS Number
– 2969213-59-8
Molecular Weight
– 513.77
SMILES
– CS(=O)(N(C1CCOCC1)C2=C(C=C(C(C(NC3=CC(F)=C(C(F)=C3)Cl)=O)=C2)Cl)Cl)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Phosphodiesterase (PDE)
Isoform
– Autotaxin
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
