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Product Description
– ATR-IN-8 is a potent inhibitor of ATR. ATR is a key enzyme in the homologous recombination repair pathway and belongs to the PIKK family. ATR-IN-8 has the potential for the research of cancer diseases (extracted from patent WO2021143821A1, compound 3)[1].
Web ID
– HY-142924
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H22N6O2S
References
– [1]Li Xin, et al. Thickened heteroaryl derivatives, their preparation methods and their application in medicine. Patent WO2021143821A1.
CAS Number
– 2672511-20-3
Molecular Weight
– 410.49
SMILES
– N=S1(C2(CC2)C3=NC(C4=C5C(NC=C5)=NC=C4)=NC(N6[C@@H](COCC6)C)=C3C1)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ATM/ATR
Pathway
– Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
