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ATR-IN-22
SKU
HY-153400-Get quote
Category Reference compound
Tags ATM/ATR, Cancer, Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Products Details
Product Description
– ATR-IN-22 (Compound 34) is an orally active ATR inhibitor. ATR-IN-22 inhibits MIAPaCa-2 proliferation (IC50 <1 μM). ATR-IN-22 shows anti-tumor activity in colon cancer[1].
Web ID
– HY-153400
Shipping
– Room temperature
Molecular Formula
– C25H31N7O
References
– [1]Xie, Yuli, et al. Naphthyridine derivative as ATR inhibitor and method for preparing same. Patent. WO2023016529. 2023-02-16.
CAS Number
– 2905312-07-2
Molecular Weight
– 445.56
SMILES
– N#CC1(CCC(CC1)N(C)C)C2=CC(N3[C@@H](COCC3)C)=NC4=C2C=CN=C4C5=NNC=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ATM/ATR
Pathway
– Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.