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Products Details
Product Description
– ATR-IN-21 (compound 60) is a potent ATR inhibitor with an IC50 value of <1000 nM[1].
Web ID
– HY-153393
Shipping
– Room temperature
Molecular Formula
– C23H27N7O
References
– [1]YuLi Xie, et al. Naphthyridine derivative as atr inhibitor and method for preparing same. WO2023016529A1.
CAS Number
– 2905312-17-4
Molecular Weight
– 417.51
SMILES
– N#CC1(CCC(CC1)N)C2=CC(N3[C@@H](COCC3)C)=NC4=C2C=CN=C4C5=NNC=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ATM/ATR
Isoform
– ATR
Pathway
– Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
