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Products Details
Product Description
– ATR-IN-17 (compound 88) is a potent ATR kinase inhibitor. ATR-IN-17 shows good anticancer activity in LoVo cells, with an IC50 of 1 nM[1].
Web ID
– HY-147569
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H28N6O2S
References
– [1]Bo Shan, et al. Atr inhibitors and uses thereof. WO2022028598A1.
CAS Number
– 2761194-15-2
Molecular Weight
– 440.56
SMILES
– CC1=NN=C(C1)C2=NSC3=C2N=C(C=C3C4(CCCCC4)C(N)=O)N5CCOC[C@H]5C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ATM/ATR
Isoform
– ATR
Pathway
– Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
