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ATP-13C10,15N5 (disodium)
$900
Only 1000 item(s) left in stock.
Products Details
Product Description
– ATP-13C10,15N5 (disodium) is a 13C-labeled and 15N-labeled ATP (HY-B2176). ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation[1][2][3][4].
Web ID
– HY-B2176S1
Storage Temperature
– Solution, -20°C, 2 years
Shipping
– Blue Ice
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– 13C10H16 15N5Na2O13P3
References
– [1]Swennen EL, et al. Immunoregulatory effects of adenosine 5′-triphosphate on cytokine release from stimulated whole blood. Eur J Immunol. 2005 Mar;35(3):852-8.|[2]M J L Bours, et al. Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther. 2006 Nov;112(2):358-404.|[3]Shuo Xu, et al. Doxycycline inhibits NAcht Leucine-rich repeat Protein 3 inflammasome activation and interleukin-1β production induced by Porphyromonas gingivalis-lipopolysaccharide and adenosine triphosphate in human gingival fibroblasts. Arch Oral Biol. 2019 Nov;107:104514.|[4]Yang Xiang, et al. Adenosine-5′-Triphosphate (ATP) Protects Mice against Bacterial Infection by Activation of the NLRP3 Inflammasome. PLoS One. 2013; 8(5): e63759.
Molecular Weight
– 568.05
Compound Purity
– 97.0
SMILES
– O=P(O)(O)OP(OP(O[13CH2][13C@H]1O[13C@@H]([15N]2[13C]3=[15N][13CH]=[15N][13C]([15NH2])=[13C]3[15N]=[13CH]2)[13C@H](O)[13C@@H]1O)(O)=O)(O)=O.[Na].[Na]
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
