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ATP
$60 – $96
Products Details
Product Description
– ATP (Adenosine 5′-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation[1][2].
Web ID
– HY-B2176
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C10H16N5O13P3
Citations
– . 2022 Nov 4.|ACS Nano. 2023 Nov 21.|Acta Pharmacol Sin. 2022 Jan 12.|Aging (Albany NY). 2021 Mar 10;13(6):8588-8598.|Aging (Albany NY). 2021 Sep 28;13(18):22588-22610.|Anal Chim Acta. 18 October 2021, 339180.|Antioxidants (Basel). 2022, 11(12), 2315.|Antioxidants (Basel). 2023 Jun 19, 12(6), 1304.|Arch Oral Biol. 2019 Aug 2;107:104514.|Biochemistry. 2023 Nov 10.|Biochim Biophys Acta Mol Basis Dis. 2023 Sep 23;166895.|Biochim Biophys Acta Mol Cell Res. 2023 Sep 18;119595.|Bioorgan Med Chem. 2021 Jan 1;29:115899.|Biosens Bioelectron. 2021 Apr 15;178:113025.|Cancer Cell Int. 2023 May 9;23(1):87.|Carbohyd Polym. 2020 Jun 1;237:116163.|Cell Death Differ. 2021 Sep 11.|Cell Death Dis. 2021 Dec 14;12(12):1159.|Cell Death Dis. 2022 Oct 8;13(10):860.|Cell Death Dis. 2020 Feb 18;11(2):132. |Cell Prolif. 2023 Apr 21;e13442.|Cell Rep. 2021 Aug 10;36(6):109516.|Clin Oral Investig. 2023 Feb 3.|Crit Care. 2021 Oct 12;25(1):356.|Eur J Pharmacol. 2021 Dec 29;174729.|Eur J Pharmacol. 2023 Mar 24;947:175681.|Front Neurosci. 2022 Jun 7;16:901688.|Int Immunopharmacol. 2023 Jan 25;116:109747.|Int J Dev Neurosci. 2022 Nov 7.|J Ethnopharmacol. 2023 Nov 8:117388.|J Virol. 2023 Mar 6;e0000323.|Life Sci. 2021 Feb 9;119192.|Mol Cell. 2022 Apr 14:S1097-2765(22)00290-8.|Mol Cell. 2023 May 19;S1097-2765(23)00324-6.|Nutrients. 2021, 13(12), 4462.|Oral Dis. 2020 Sep 28. |Phytomedicine. 2023 Nov 8, 155193.|Protein Cell. 2021 Oct 22;1-21.|Research Square Preprint. 2021 Jul.|Research Square Preprint. 2022 Feb.|Research Square Preprint. 2022 May.|Research Square Preprint. 2023 Sep 8.|SSRN. 2023 May 12.|SSRN. 6 Dec 2022.|Transl Res. 2022.|Cell Death Dis. 2020 Jan 30;11(1):78.|Cell Death Dis. 2023 Mar 1;14(3):174.|Research Square Preprint. 2020 Dec.|Int Immunopharmacol. 2023 Feb 21;117:109917.
References
– [1]M J L Bours, et al. Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther. 2006 Nov;112(2):358-404.|[2]Shuo Xu, et al. Doxycycline inhibits NAcht Leucine-rich repeat Protein 3 inflammasome activation and interleukin-1β production induced by Porphyromonas gingivalis-lipopolysaccharide and adenosine triphosphate in human gingival fibroblasts. Arch Oral Biol. 2019 Nov;107:104514.|[3]Yang Xiang, et al. Adenosine-5′-Triphosphate (ATP) Protects Mice against Bacterial Infection by Activation of the NLRP3 Inflammasome. PLoS One. 2013; 8(5): e63759.|[4]Swennen EL, et al. Immunoregulatory effects of adenosine 5′-triphosphate on cytokine release from stimulated whole blood. Eur J Immunol. 2005 Mar;35(3):852-8.
CAS Number
– 56-65-5
Molecular Weight
– 507.18
Compound Purity
– 99.62
SMILES
– O=P(O)(O)OP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@H](O)[C@@H]1O)(O)=O)(O)=O
Clinical Information
– Launched
Research Area
– Metabolic Disease; Inflammation/Immunology
Solubility
– H2O : ≥ 100 mg/mL
Target
– Endogenous Metabolite
Isoform
– Human Endogenous Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
