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Atosiban (acetate)

$84$264

Products Details

Product Description

– Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research[1].

Web ID

– HY-17572A

Storage Temperature

– -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C45H71N11O14S2

Citations

– J Pharm Biomed Anal. 11 December 2021, 114518.|Front Neurosci. 2021 Sep 10;15:723064.|J Pharm Biomed Anal. 2022: 115156.

References

– [1]Sanu O, et al. Critical appraisal and clinical utility of atosiban in the management of preterm labor. Ther Clin Risk Manag. 2010 Apr 26;6:191-9.|[2]Philip J Ryan, et al. Oxytocin-receptor-expressing Neurons in the Parabrachial Nucleus Regulate Fluid Intake. Nat Neurosci. 2017 Dec;20(12):1722-1733.

CAS Number

– 914453-95-5

Molecular Weight

– 1054.24

Compound Purity

– 99.88

SMILES

– O=C([C@H](CSSCCC(N[C@@H](C1=O)CC2=CC=C(OCC)C=C2)=O)NC([C@@H](NC(C(NC([C@](N1)([H])[C@@H](C)CC)=O)[C@H](O)C)=O)CC(N)=O)=O)N(CCC3)[C@@H]3C(N[C@@H](CCCN)C(NCC(N)=O)=O)=O.OC(C)=O

Clinical Information

– Launched

Research Area

– Cancer; Endocrinology

Solubility

– DMSO : 100 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)

Target

– Oxytocin Receptor;Vasopressin Receptor

Pathway

– GPCR/G Protein

Product type

– Peptides

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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