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Products Details
Product Description
– ATM Inhibitor-9 (Compd 7a) is a potent ATM inhibitor with IC505 nM for ATM kinase, useful in cancer research[1].
Web ID
– HY-155091
Shipping
– Room temperature
Molecular Formula
– C25H32N6O2
References
– [1]Dexin Deng, et al. Discovery and Evaluation of 3-Quinoxalin Urea Derivatives as Potent, Selective, and Orally Available ATM Inhibitors Combined with Chemotherapy for the Treatment of Cancer via Goal-Oriented Molecule Generation and Virtual Screening. J Med Chem. 2023 Jul 27;66(14):9495-9518.
Molecular Weight
– 448.56
SMILES
– O=C(NC1=NC2=CC(C3=CC=C(N=C3)OCCCN(C)C)=CC=C2N=C1)NC4CCCCC4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ATM/ATR
Pathway
– Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
