Download Files:
Products Details
Product Description
– OHM 11638 (Atilmotin), an analogue of the (1-14) fragment of porcine motilin, is a motilin receptor agonist with a pKd of 8.94 for the motilin receptor. OHM 11638 affects esophageal, lower esophageal sphincter (LES), and gastric motility. OHM 11638 increases LES and gastric pressures, OHM 11638 can be used as prokinetic agents[1][2].
Web ID
– HY-106258
Shipping
– Room temperature
Molecular Formula
– C86H135N20O19+
References
– [1]Peeters T L. Motilin and the Discovery and Development of Motilinomimetics. Old Herborn University Seminar Monograph. INSTITUTE FOR MICROBIOLOGY AND BIOCHEMISTRY, 1997, 9: 77-87.|[2]Korimilli A, Parkman HP. Effect of atilmotin, a motilin receptor agonist, on esophageal, lower esophageal sphincter, and gastric pressures. Dig Dis Sci. 2010 Feb;55(2):300-6.
CAS Number
– 533927-56-9
Molecular Weight
– 1753.11
SMILES
– C[N+](C)(C)[C@@H](CC1=CC=CC=C1)C(N[C@@H](C(C)C)C(N2[C@@H](CCC2)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(N[C@@H]([C@H](O)C)C(N[C@H](C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCCCN)=O)=O)=O)=O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Motilin Receptor
Pathway
– GPCR/G Protein
Product type
– Peptides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
