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ASP7663

$52$770

Products Details

Product Description

– ASP7663 is an orally active and selective TRPA1 agonist. ASP7663 exerts both anti-constipation and anti-abdominal pain actions[1][2].

Web ID

– HY-101907

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C14H14FNO3

References

– [1]Ryosuke Kojima, et al. Effects of Novel TRPA1 Receptor Agonist ASP7663 in Models of Drug-Induced Constipation and Visceral Pain. Eur J Pharmacol. 2014 Jan 15;723:288-93.|[2]Yao Lu, et al. Transient Receptor Potential Ankyrin 1 Activation Within the Cardiac Myocyte Limits Ischemia-reperfusion Injury in Rodents. Anesthesiology. 2016 Dec;125(6):1171-1180.

CAS Number

– 1190217-35-6

Molecular Weight

– 263.26

Compound Purity

– 99.16

SMILES

– O=C(O)/C=C1C(N(CC(C)C)C2=C/1C=CC=C2F)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– DMSO : 50 mg/mL (ultrasonic)

Target

– TRP Channel

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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