Download Files:
ASP-4058
SKU
HY-111021-10 mg
Category Reference compound
Tags GPCR/G Protein, Inflammation/Immunology, LPL Receptor
$360 – $3,050
Products Details
Product Description
– ASP-4058 is a next-generation, selective and oral bioactive agonist for Sphingosine 1-Phosphate receptors 1 and 5 (S1P1 and S1P5), ameliorates rodent experimental autoimmune encephalomyelitis with a favorable safety profile[1].
Web ID
– HY-111021
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H12F6N4O2
References
– [1]Rie Yamamoto, et al. ASP4058, a Novel Agonist for Sphingosine 1-Phosphate Receptors 1 and 5, Ameliorates Rodent Experimental Autoimmune Encephalomyelitis with a Favorable Safety Profile. PLoS One. 2014 Oct 27;9(10):e110819.
CAS Number
– 952565-91-2
Molecular Weight
– 442.31
Compound Purity
– 99.43
SMILES
– C[C@H](OC1=CC=C(C2=NC(C3=CC=C4N=CNC4=C3)=NO2)C=C1C(F)(F)F)C(F)(F)F
Clinical Information
– Phase 1
Research Area
– Inflammation/Immunology
Solubility
– DMSO : ≥ 50 mg/mL
Target
– LPL Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.