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Asoprisnil
SKU
HY-119433-1 mg
Category Reference compound
Tags Endocrinology, Progesterone Receptor, Vitamin D Related/Nuclear Receptor
$300
Only 1000 item(s) left in stock.
Products Details
Product Description
– Asoprisnil (J867), a selective progesterone receptor modulator, exhibits mixed progesterone agonist and antagonist effects on various progesterone targeted tissues in animal and human[1].
Web ID
– HY-119433
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C28H35NO4
References
– [1]Stewart EA, et al. Safety and efficacy of the selective progesterone receptor modulator asoprisnil for heavy menstrual bleeding with uterine fibroids: pooled analysis of two 12-month, placebo-controlled, randomized trials. Hum Reprod. 2019 Apr 1;34(4):623-634.|[2]Wu XL, et al. Postcoital administration of asoprisnil inhibited embryo implantation and disturbed ultrastructure of endometrium in implantation window in mice. J Huazhong Univ Sci Technolog Med Sci. 2013 Apr;33(2):277-283.
CAS Number
– 199396-76-4
Molecular Weight
– 449.58
Compound Purity
– 98.30
SMILES
– C[C@@]12[C@@](OC)(CC[C@]1([C@@]3(CCC4=CC(CCC4=C3[C@H](C2)C5=CC=C(C=C5)/C=N/O)=O)[H])[H])COC
Clinical Information
– Phase 3
Research Area
– Endocrinology
Solubility
– 10 mM in DMSO
Target
– Progesterone Receptor
Pathway
– Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.