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Products Details
Product Description
– Ascochlorin A is a novel and potent hDHODH inhibitor (KD = 3.29 μM) for research of triple-negative breast cancer.
Web ID
– HY-139632
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H31ClO4
References
– [1]Luo X, et al. Exploring Marine-Derived Ascochlorins as Novel Human Dihydroorotate Dehydrogenase Inhibitors for Treatment of Triple-Negative Breast Cancer. J Med Chem. 2021 Sep 23;64(18):13918-13932.
CAS Number
– 2550720-02-8
Molecular Weight
– 406.94
SMILES
– OC(C(C=O)=C(C(Cl)=C1O)C)=C1C/C=C(C)/CC[C@H]2C(C)([C@H](CCC2=C)O)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Dihydroorotate Dehydrogenase;DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
