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AS604872

SKU HY-118388-Get quote Category Tags , ,

Products Details

Product Description

– AS604872 is an orally active, potent and selective prostaglandin F2α receptor (FP) antagonist with a Ki of 35 nM in humans, 158 nM in rats and 323 nM in mice. AS604872 inhibits contractions and delays labour[1].

Web ID

– HY-118388

Shipping

– Room temperature

Molecular Formula

– C28H25N3O3S2

References

– [1]Rocco Cirillo, et al. Arrest of preterm labor in rat and mouse by an oral and selective nonprostanoid antagonist of the prostaglandin F2alpha receptor (FP). Am J Obstet Gynecol. 2007 Jul;197(1):54.e1-9.

CAS Number

– 612532-48-6

Molecular Weight

– 515.65

SMILES

– O=C([C@H]1N(CCS1)S(=O)(C2=CC=C(C3=CC=CC=C3)C=C2)=O)N[C@@H](C4=CC=CC=N4)C5=CC=CC=C5

Clinical Information

– No Development Reported

Research Area

– Endocrinology

Solubility

– 10 mM in DMSO

Target

– Prostaglandin Receptor

Pathway

– GPCR/G Protein

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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